ActiTrexx GmbH

Gründung: 28.09.2022
Rechtsform: GmbH
Anzahl Mitarbeiter: 9

Sektoren der Gesundheitswirtschaft:
Technologieschwerpunkt / Versorgungssektor: Biotechnologie

Wir sind: Biotechunternehmen

Kernkompetenz des Unternehmens: We are a clinical-stage company specializing in the activation of regulatory T cells and the development of groundbreaking cellular and biologic therapies. Our focus is on addressing T cell-mediated autoimmune and autoinflammatory diseases.

Through our lead cellular product, Actileucel, we aim to revolutionize the treatment landscape by targeting conditions like Graft-versus-Host Disease (GvHD), a severe complication occurring when donor immune cells attack the recipient's tissues after allogeneic stem cell transplant.

Actileucel, designed to prevent and treat GvHD, effectively utilizes the capabilities of activated regulatory T cells from unmatched third-party donors, aimed to provide a safer and more effective therapy compared to conventional treatments such as immunosuppressants.

Our expertise extends beyond therapy development to efficient manufacturing processes, ensuring timely solutions to pressing medical challenges.

Classified as an Advanced Therapy Medicinal Product (ATMP), Actileucel is manufactured in a lean and fast process, allowing a 24h readiness and a highly competitive pricing. Recently, we achieved a significant milestone by treating the first patient with Actileucel, marking a crucial step forward in advancing treatment options.

Wir bieten folgende Kooperationen / Kooperationspartnerschaften: 
Research & Development

Wir bieten folgende Kooperationen / Kooperationspartnerschaften: 

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Prof. Dr. Andrea Tüttenberg , Co-Founder and CEO

Prof. Dr. Andrea Tüttenberg


  • Dr. Andrea Tüttenberg, medical doctor by training and professional in the field of dermatology and immunooncology, possesses a rich and multifaceted career. She completed her medical education at the University of Mainz, Germany, with additional studies in Zürich, Switzerland, and Montreal, Canada. She earned her Doctoral Degree in human medicine in 1998 and completed her Habilitation in 2010, both from Johannes Gutenberg-University Mainz. Since 2017, she holds the position of Associate Professor at the Department of Dermatology, UMC Mainz, where her expertise contributes significantly to both academic research and clinical practice.
  • Currently serving as the CEO of ActiTrexx GmbH, Dr. Tüttenberg has demonstrated exceptional leadership and strategic acumen in steering the company towards innovative solutions in healthcare.
  • In the past, Dr. Tüttenberg has led various pivotal projects, including serving as the Project Leader of the prestigious GO-Bio project since 2016. Her commitment to advancing immunotherapy and understanding the complexities of the tumor microenvironment is evident through her role as Group Leader of Immunooncology at the Department of Dermatology, UMC Mainz, since 2013.
  • Throughout her career, Dr. Tüttenberg has been honored with numerous awards, including the GO-Bio I and II grants from the Federal Ministry of Education and Research, the Dermato-Oncology Award from the Society of Dermatological Research, and the 2022 Winner Pioniergeist Competition RLP. Her dedication to mentorship and fostering young talent is reflected in her roles as a mentor for various programs, such as the MeMentUM-Mentoring Program at the University Medical Center Mainz.
  • Dr. Tüttenberg has published extensively in esteemed journals, contributing significantly to the advancement of dermatology and immunology. Her research has been supported by grants exceeding €5 million from prestigious organizations like the German Research Foundation and the German Consortium for Translational Cancer Research (DKTK).

    ActiTrexx GmbH - c/o University Medical Center Mainz - Johannes Gutenberg-University Mainz

    Langenbeckstr. 1
    Building 401
    55131 Mainz

    Telefon: 06131 / 17 29 17

    Warum engagieren Sie sich
    im InnoNet-Netzwerk?

    1. Visibility and Exposure: We can showcase our products, therapies, and achievements to a broad audience, enhancing brand awareness. 2. Networking Opportunities: It facilitates connections with other companies, research institutions, and experts, fostering potential partnerships, collaborations, and projects. 3. Knowledge Exchange: We can learn from and share expertise with other members, leading to mutual enrichment and development. 4. Access to Resources: The network may provide access to funding, experts, technical support, and infrastructure, aiding in the advancement of our therapies and scaling our business. 5. Cross-Industry Perspectives: Participation exposes us to diverse perspectives and innovations, sparking new ideas and approaches to our challenges and goals.


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